Impact of CPAP Therapy on Occupational Injuries (Sleep Apnea and Cardiovascular Risk)

Project number: 
14-058
Approval date: 
Monday, July 21, 2014
Principal Investigator: 
Fox,Nurit
Institution: 
University of British Columbia (UBC)
Funding Agency: 
Canadian Institutes of Health Research(CIHR)
Datasets requested: 
Deaths (BC Vital Statistics Agency)
Cardiac Services BC
Consolidation registry (Ministry of Health)
Hospital Separations (BC Ministry of Health)
Research objective: 

The research question is whether obstructive sleep apnea (OSA) is an independent risk factor for the development of cardiovascular disease.

The hypothesis is that patients with OSA will have an increased requirement for revascularization (PTCA, CABG) and valvular procedures even after controlling for a variety of potential confounders (e.g. BMI, gender, previous cardiac disease). Similarly, we hypothesize that patients with OSA will have increased hospitalizations for cardiac complications (such as myocardial infarctions), and an increased mortality related to CVD.

We hypothesize that these risks will increase with increased OSA severity.


Page last revised: December 5, 2017