Improving the diagnosis of fetal growth restriction with the new INTERGROWTH-21st growth standard

Project number: 
Approval date: 
Wednesday, May 30, 2018
Principal Investigator: 
University of British Columbia (UBC)
Funding Agency: 
Not Available
Datasets requested: 
Medical Services Plan (BC Ministry of Health)
Consolidation file (BC Ministry of Health)
Perinatal Services BC
Deaths (BC Vital Statistics Agency)
Consolidation - demographic (Ministry of Health)
Stillbirths (BC Vital Statistics Agency)
Hospital Separations (BC Ministry of Health)
Early Development Instrument (Human Early Learning Partnership)
Research objective: 

1) Research Questions:
a) The primary objective of this study is to link the INTERGROWTH 21st Fetal Growth chart percentiles with risks of adverse short- and longer-term child health outcomes in order to determine the optimal percentile thresholds for identifying high-risk fetuses.
b) Our secondary objective is to determine the extent to which the optimal risk thresholds differ by gestational age.

2) Hypotheses:
We hypothesize that risks of both short and longer-term outcomes will be increased at the extreme percentiles of the INTERGROWTH chart percentiles, and that the ranges at which risks are lowest will be more narrow at younger gestational ages

Page last revised: August 29, 2018