Pattern and outcomes associated with inappropriate use of short-acting beta-agonists in asthma

Project number: 
15-101
Approval date: 
Monday, September 28, 2015
Principal Investigator: 
Sadatsafavi,Mohsen
Institution: 
University of British Columbia (UBC)
Funding Agency: 
Not Available
Datasets requested: 
Deaths (BC Vital Statistics Agency)
Medical Services Plan (BC Ministry of Health)
Consolidation - demographic (Ministry of Health)
PharmaNet
Hospital Separations (BC Ministry of Health)
Consolidation registry (Ministry of Health)
Births (BC Vital Statistics Agency)
consolidation - census geocodes
Research objective: 

Objectives:

Objective 1: Determine the pattern and trend of short-acting beta-agonist (SABA) use in relation with the use of inhaled corticosteroids (ICS) in British Columbia (BC) between 1997 and 2014.

Objective 2: Determine the predictors of inappropriate use of SABAs.

Objective 3: Determine the outcomes associated with the inappropriate use of SABAs in relation with ICS.

Hypotheses:

Hypothesis 1: There continues to be inappropriate use of SABAs in BC across the study period.

Hypothesis 2: Factors such as socio-economic status (SES), demographic factors (sex), and access to care (generalist versus specialist care) are associated with inappropriate use of SABAs.

Hypothesis 3: Inappropriate use of SABAs has been associated with preventable hospital admissions or exacerbations requiring systemic corticosteroids.

Publications: 

Journal Publication

  • Predictors of inappropriate and excessive use of reliever medications in asthma: a 12-year population-based study. Tavakoli H, Fitzgerald JM, Lynd LD, Sadatsafavi M. BMC Pulmonary Medicine, volume 18, Article number: 33 (2018).

Page last revised: September 2, 2019