Would patients with non-obstructive coronary artery disease benefit from cardiac medication?


A woman having her heart rate measured

Data access has been approved for a research project which will use linked administrative data to examine cardiac medication use in a population of patients in British Columbia.

The research team is led by Dr Tara Sedlak, Clinical Assistant Professor and Cardiologist at the University of British Columbia (UBC).

The study will examine cardiac medication use in a population of patients in BC with both acute coronary syndrome (ACS) and stable angina to determine if there is a difference in major adverse cardiovascular events in patients with non-obstructive coronary artery disease (CAD) who are on cardiac medications compared to those who discontinue and/or never start medications.

“Current research suggests that non-obstructive CAD is not treated as aggressively as obstructive CAD post angiography,” says Internal Medicine student, Dr Shannon Galway. “To date, no one has examined whether these patterns of medication use in non-obstructive CAD are predictive of cardiac events. Our study will compare patients with both ACS and/or stable angina to determine whether different patterns of use predict clinical outcomes.”

The project forms part of Dr Galway’s residency training in the Faculty of Medicine at UBC. The results of the study may change guidelines for medications in patients with non-obstructive coronary artery disease.

Population Data BC will link BC Ministry of Health PharmaNet data and Cardiac Services BC data for the project.